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Alexion Pharmaceuticals AAMF, Ireland

Alexion Pharmaceuticals AAMF, Ireland

    • CLIENT:
    • Alexion Pharmaceuticals
    • PM Group
    • DPS
    • PROJECT:
    • Alexion AAMF Biologics Manufacturing Facility
    • VALUE:
    • €14.5m
    • SECTOR:
    • Life Sciences
    • Westmeath, Ireland


Kirby was appointed to complete full installation of mechanical, process pipework and electrical/instrumentation services on a new biological purification suite for Alexion Pharmaceuticals. The works were completed on a three storey development, as well as warehouse expansion to provide additional capacity at an existing fill-finish facility. A piperack was also installed from the existing CUB building to the new purification suite.

Kirby utilised Building Information Modelling (BIM) to successfully integrate all elements of design across services and ensure high quality installation. Kirby implemented LEAN construction techniques throughout the project. All pipework was prefabricated off-site, which optimised project efficiency. Labour on site peaked at 89.


Kirby scope of works included the installation and commissioning of mechanical, process pipework and electrical/instrumentation services.

The electrical and instrumentation systems installed by Kirby included:

• MV Distribution
• LV Distribution
• Generator
• General and Emergency Lighting
• General Service Power
• Mechanical Plant Service Power
• Fire Detection and Alarm
• Access Control, Intruder and CCTV
• Earthing and Bonding
• Voice and Data Distribution
• Lightning Protection
• Impulse Tubing
• Profibus

The mechanical systems installed by Kirby included:

• Chilled Water
• Low Temperature Hot Water
• Laboratory Gases
• Smoke and Heat Exhaust Ventilation
• Supply and Extract Ventilation Distribution
• VRF Air Conditioning
• Leak Detection
• Server Room Air Conditioning
• Bioprocess Waste
• Clean In Place (CIP)
• Clean Steam
• Humidification Water
• Nitrogen
• Process Air
• Process Chilled Water
• RO Water
• Solvent / Solvent Waste
• Vacuum
• Water for Injection (WFI)
• Purified Water
• Hot Process Water
• Compressed Air
• Instrument Air
• Product Lines
• Steam
• Process Waste
• Soils and Wastes
• Domestic Water Services
• Stainless Exhaust

Installed plant items included MV switchgear and cable, LV switchgear, UPS systems and instrumentation.

The total project meterage consisted of 300,000m of cable, 8,500m of containment, 500 number of instruments, 1,000 number of loops, 300 number of calibrations, 10,000m of impulse piping, 1,000 number of I/O points, 5,000m of black utilities pipework, 155m of plastic pipework, 1,500m of copper pipework, 3,300m of clean utilities pipework and 5,580m² ductwork.